Ruoting Yang

Journey to 
Systems Biology 

My Research 

Ruoting Yang  Ph.D.

Postdoctoral Fellow in Systems Biology
Department of Chemical Engineering
Institute for Collaborative Biotechnologies
University of California, Santa Barbara

My research focuses on identifying novel diagnostic biomarkers for complex diseases by integrating and analyzing high-throughput "omics" data that implicates disease-disturbed functions in DNAs, RNAs, proteins, and metabolites.  I aim to assemble a multi-level network interlinked with common "disease modules" across multiple tissues, genotypes, and species. Collaborating closely with experimental groups, I merged first-hand experimental data collected with cutting-edge technologies and state-of-the-art computational techniques.  As a result, the insights provided by my clinical systems biology research can impose a "top-down" systematic perspective on current understanding of biological processes, and potentially revise traditional therapies for complex diseases, such as Post-traumatic Stress Disorder (PTSD), cancer, prion diseases, and circadian rhythm disorders.  

Past and Current Research

1. Genetic biomarker identification and disease network construction

2. "Bottom-up" modeling in a control engineering framework

3. "Omics" data analysis, integration, and visualization

4. Control design in drug delivery

5. Biomimetic robotics
 


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